| Humboldt is located about 8 miles north of I-40 and Jackson. If you are on I-40 headed west towards Memphis, take exit 80-B North on the Hwy 45 By-Pass. If you are on I-40 headed east towards Nashville, take exit 80-B North on the Hwy 45 By-pass. This will take you straight in to Humboldt.
If you're coming in from the north, take Hwy 45 south, which runs directly into Humboldt.
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